Diuretic effect of Phyllantus niruri “chanca piedra” and excretion of sodium levels in Rattus rattus var. albinus

Authors

  • Segundo Felix Castillo Viera Universidad Nacional de Trujillo, La Libertad, Perú
  • Ericson Felix Castillo Saavedra Universidad San Pedro, Ancash, Perú
  • Cecilia Elizabeth Reyes Alfaro Universidad Nacional de Trujillo, La Libertad, Perú

DOI:

https://doi.org/10.18050/revucv-scientia.v3i1.892

Keywords:

Phyllanthus niruri, Diuretic effect, Sodium levels

Abstract

This report was oriented on determinating if Phyllanthus niruri “chanca piedra” presents on diuresis and sodium levels in Rattus rattus var. albinus. This study was conformed by 30 rats divided in three treatments' groups, these received treatment previous for 6 hours with physiology saline solution, 8mg/Kg/pc of hydrochlorothiazide y 10gr/Kg/pc of Phyllanthus niruri extract to patron and problem respectively. Phyllanthus niruri presents diuretic effect with a urinary volume of 10.2 mL and these results are better than control group (4.66 mL) and patron group (8.31 mL) with significative difference (p<0.05). Phyllanthus niruri presents the best sodium levels excreted in contrast with control group and patron group with significative difference (p<0.05). In conclusion presents diuretic effect and increase sodium levels excreted in Rattus rattus var.albinus.

Published

2011-06-30

How to Cite

Castillo Viera, S. F., Castillo Saavedra, E. F., & Reyes Alfaro, C. E. (2011). Diuretic effect of Phyllantus niruri “chanca piedra” and excretion of sodium levels in Rattus rattus var. albinus. UCV-Scientia, 3(1), 11–17. https://doi.org/10.18050/revucv-scientia.v3i1.892

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