Phytoconstituyents of Glandulosa psoralea leaves and effect of infuso on glicemia in Rattus rattus var. albinus with experimental hiperglicemia

Abstract

At the present study we determined the phitoconstituyent Psoralea glandulosa leaves and its hipogliceming effect in Rattus rattus var albinos. Determination of the phitoconstituyent was used the March Phitochimestry Olga Lock adapated by Casanova.Being the following fitoconstitutives: phenoles, flavonoids, tanins. To check the hipoglicemic effect of the leaves infuse of Psoralea glandulosa 24 animals was distributed in four groups. Group I they were administered solutio of glucose for oral way to the doses of 2.5 g/kg.c.w. and derterminate the glicemi respectively by diferent time: 30, 60, 90, 120 minutes In the second group they were administered infuse by 160 mg/dL. and glucose solution and repeat the same method as first group. The group III determinate intestinal absortion with glucose solution and infuse with glucose then determinated the glucose value. Enzymatic method was used for the determinations of glucose,being that the infuse to the dose 160 mg/dL of c.w. it exercises hipoglicemic effect,being statistically this value significant ( P< 0.05). We conclude that the infuse of leaves of Psoralea glandulosa has hipoglicemic effect.