Acantosis nigricans associated to malignity

Abstract

The Acanthosis nigricans is characterized to present hyperpigmentation, hyperqueratosis and presence of multiple papillomatosis that affects mainly in symmetrical form the cutaneous folds. According to etiology it is classified in two great groups: benign and malignant. In the present article we described a case of a 42 years old woman affected of a carcinoma poorly differentiated diffuse type in stomach and development Acantosis Nigricans. The pathophysiology is reviewed in addition and the possible common pathogenic mechanism of these dermathologic manifestations in relation to neoplasia.