Epidemiological clinical profile of Guillain Barré Syndrome. Hospital Belén de Trujillo, Perú 2009 - 2019

Abstract

Objective: To characterize the epidemiological clinical profile of Guillain Barré Syndrome (GBS) in patients admitted to the Hospital Belén de Trujillo in the period 2009 to 2019. Material and Methods: Descriptive study of quantitative approach; 108 clinical records and 70 epidemiological clinical research records of patient surveillance with GBS were established since the end of 2017. Results: It was identified that in 2019 the incidence was higher (0.176), with a lethality of 10.4. The male gender was the most affected in 62 %; the range of 20 to 39 years of age was predominant with 32.4%, of greater urban origin (64 %). Upper respiratory infections were the main antecedent in 41 % of cases. The characteristic clinic was compromise of muscular strength, with ascending, symmetric paralysis and involvement of osteotendinous reflexes with 100 %, 61 %, 65 % and 84 % respectively. The 100 % had motor involvement; the most reported complication was respiratory failure (RF) with 21%; the most commonly used treatment was immunoglobulin in 72% and the study with the highest application was the cerebrospinal fluid test (71%). Conclusion: The GBS had a greater incidence in the year 2019, it was more frequent in men, preponderant of 20 – 39 years of age, mostly of urban origin, with clinical characteristic of ascending, symmetrical paralysis, of preferential involvement of the motor area, being the RF, its main complication and the main therapeutic alternative is immunoglobulin.